The Liposonix system focuses high-intensityfocused ultrasound energy at a precise depth (1.3 cm) within the targeted adipose tissue in the abdomen and flanks, without harming the skin or surrounding tissues and organs. This causes thermal coagulation of adipose tissue within the focal zone of the ultrasound beam. The destroyed tissue and released triglycerides are engulfed and removed by macrophages that are drawn to the treated area by chemotactic signals. The lipid-laden macrophages then move through the lymphatic system to the liver, where the lipids are processed by the body’s normal biochemical pathways. Once processed by the liver, the energy from the lipids may be used by the body directly or, as with any fat, may be stored by the body in adipose tissue if the energy is not required immediately. Adipocytes that are destroyed in the treated area are no longer available to store fat. The damaged tissue in the treated area is resorbed over a period of approximately 8 to 12 weeks, which can yield an aesthetic body-contouring effect.