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LipoSonix Technology
LipoSonix is taking a rigorous, science-based approach to technology development. Patient safety and integrity of
clinical data are of paramount importance in all clinical studies conducted by the company
LipoSonix achieves targeted reduction of adipose tissue by precisely focusing high intensity ultrasound energy to cause
disruption. A custom designed ultrasound transducer delivers energy across the skin surface
at a relatively low intensity, but brings this energy to a sharp focus in the subcutaneous fat. At the skin surface,
the intensity of the ultrasound energy is low enough so that no damage occurs. The focusing of the ultrasound beam at
specific depths beneath the epidermis, combined with proprietary application techniques, results in adipose tissue
disruption.¹
Once adipocytes have been disrupted, chemotactic signals activate the body's inflammatory response mechanisms. Macrophage
cells are attracted to the area to engulf and transport the lipids and cell debris. This results in an overall reduction
in local adipose tissue volume. ² The goal is to achieve precision that will result in effective non-invasive body
sculpting.
LipoSonix has exclusively licensed two important patents, including the seminal patent in the field. The company has filed
a number of additional patent applications on related methods and technology, and continues to work to expand and strengthen
this portfolio.
Clinical Results
LipoSonix' initial efforts involved extensive pre-clinical in vitro and in vivo testing to demonstrate proof of principle
and refine specific treatment protocols. Initial human feasibility studies were performed on patients undergoing
abdominoplasty surgery, allowing for detailed evaluation of the patho-physiological process. This evaluation was accomplished
through evaluation of extensive blood panels, gross pathology, histological analysis, and non-invasive imaging
(including computed tomography (CT), magnetic resonance imaging (MRI), and ultrasound.) ²
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LipoSonix Abstracts
Plastic Surgery 2005
M0002 (PDF, 88K)
M0003 (PDF, 32K)
American Academy of Dermatology 2006
M0008 (PDF, 212K)
American Society for Aesthetic Plastic Surgery 2006
M0011 (PDF, 184K)
M0012 (PDF, 204K)
Plastic Surgery 2006
M0013 (PDF, 112K)
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