LipoSonix: Non-invasive Body Sculpting


LipoSonix Procedure LipoSonix Technology

LipoSonix is taking a rigorous, science-based approach to technology development. Patient safety and integrity of clinical data are of paramount importance in all clinical studies conducted by the company

LipoSonix achieves targeted reduction of adipose tissue by precisely focusing high intensity ultrasound energy to cause disruption. A custom designed ultrasound transducer delivers energy across the skin surface at a relatively low intensity, but brings this energy to a sharp focus in the subcutaneous fat. At the skin surface, the intensity of the ultrasound energy is low enough so that no damage occurs. The focusing of the ultrasound beam at specific depths beneath the epidermis, combined with proprietary application techniques, results in adipose tissue disruption.¹

Once adipocytes have been disrupted, chemotactic signals activate the body's inflammatory response mechanisms. Macrophage cells are attracted to the area to engulf and transport the lipids and cell debris. This results in an overall reduction in local adipose tissue volume. ² The goal is to achieve precision that will result in effective non-invasive body sculpting.

LipoSonix has exclusively licensed two important patents, including the seminal patent in the field. The company has filed a number of additional patent applications on related methods and technology, and continues to work to expand and strengthen this portfolio.



Clinical Results

LipoSonix' initial efforts involved extensive pre-clinical in vitro and in vivo testing to demonstrate proof of principle and refine specific treatment protocols. Initial human feasibility studies were performed on patients undergoing abdominoplasty surgery, allowing for detailed evaluation of the patho-physiological process. This evaluation was accomplished through evaluation of extensive blood panels, gross pathology, histological analysis, and non-invasive imaging (including computed tomography (CT), magnetic resonance imaging (MRI), and ultrasound.) ²





LipoSonix Abstracts


Plastic Surgery 2005
M0002 (PDF, 88K)      M0003 (PDF, 32K)


American Academy of Dermatology 2006
M0008 (PDF, 212K)     


American Society for Aesthetic Plastic Surgery 2006
M0011 (PDF, 184K)      M0012 (PDF, 204K)


Plastic Surgery 2006
M0013 (PDF, 112K)     



The LipoSonix system is not available for sale or use in the United States

1 Murray, E., et. al. The Use and Mechanism of Action of High-Intensity Focused Ultrasound for Adipose Tissue Removal and Non-Invasive Body Sculpting. (Abstract) ASPS Meeting Chicago, Illinois, September 2006

2 Smoller, B.R., et. al. The histopathological changes from the use of High-Intensity Focused Ultrasound (HIFU) in Adipose Tissue (Abstract) AAD Meeting, San Francisco, March 2006. JAAD;AB230:P3108, 2006

3 Murray, E., et. al Evaluation of the Acute and Chronic Systemic and Metabolic Effects from the Use of High-Intensity Focused Ultrasound for Adipose Tissue Removal and Non-Invasive Body Sculpting. (Abstract) ASPS Meeting, Chicago, Illinois, September 2005

Copyright © 2002-2008 LipoSonix, Inc. All right reserved.